Scientists at the University of Kyoto have linked Vinculin, a focal adhesion protein, with the famous YAP/TAZ pathway: its a mechanosensor that dictates cell fate based on the rigidity of the substrate

 Noriyuki Kioka’s team have provided a new window of understanding on how mechanical forces influence cell differentiation.
Continue reading “Cells probe their surroundings to transduce a mechanical signal into a genetic one”