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Crisps, CRISPR and the CRISPR-er

CRISPR_blog pic

 

Dr. Jennifer Doudna, one of the leading figures to propose the use of the adaptive bacterial immune mechanism-CRISPR/cas9 for targeted gene editing [1], was invited to King’s College London to deliver a lecture as part of the King’s International Lecture series. Continue reading “Crisps, CRISPR and the CRISPR-er”

In a pinch – cells use clathrin-coated lattice tubes to anchor themselves to the ECM during cell migration

Nadia Elkhatib and colleagues have provided evidence to explain why cells in 3D show fewer integrin rich focal adhesions compared to cells on flat surfaces.

Continue reading “In a pinch – cells use clathrin-coated lattice tubes to anchor themselves to the ECM during cell migration”

Cells probe their surroundings to transduce a mechanical signal into a genetic one

Scientists at the University of Kyoto have linked Vinculin, a focal adhesion protein, with the famous YAP/TAZ pathway: its a mechanosensor that dictates cell fate based on the rigidity of the substrate

 Noriyuki Kioka’s team have provided a new window of understanding on how mechanical forces influence cell differentiation.
Continue reading “Cells probe their surroundings to transduce a mechanical signal into a genetic one”

Top 3 of the week 20/6 to 27/6

Brexit, Brexit, Brexit

It will come as no surprise that one of the top science news (well, all news really!) stories from last week is that Britain has voted to leave the EU. Many researchers have expressed apprehension about what this could mean for their future funding, collaborations and participation in significant European research programmes. Continue reading “Top 3 of the week 20/6 to 27/6”

Top 6 of The Fortnight! 16/5 to 30/5

Howdy Readers, did you miss us? We sure missed you! We are now back and swinging and we thought we would compensate for our temporary absence with a giant edition of Top 3 Of the Week, imaginatively named Top 6 Of The Fortnight. Take an extra-comfy seat, grab an extra-large drink and get stuck into this extra-large serving of science! Continue reading “Top 6 of The Fortnight! 16/5 to 30/5”

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