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In a pinch – cells use clathrin-coated lattice tubes to anchor themselves to the ECM during cell migration

Nadia Elkhatib and colleagues have provided evidence to explain why cells in 3D show fewer integrin rich focal adhesions compared to cells on flat surfaces.

Continue reading “In a pinch – cells use clathrin-coated lattice tubes to anchor themselves to the ECM during cell migration”

Cells probe their surroundings to transduce a mechanical signal into a genetic one

Scientists at the University of Kyoto have linked Vinculin, a focal adhesion protein, with the famous YAP/TAZ pathway: its a mechanosensor that dictates cell fate based on the rigidity of the substrate

 Noriyuki Kioka’s team have provided a new window of understanding on how mechanical forces influence cell differentiation.
Continue reading “Cells probe their surroundings to transduce a mechanical signal into a genetic one”

This Week’s Top 3 Science News (8/2 to 15/2)

This Week’s Top 3 Science News aims to shine a light on the three most exciting nuggets of science that have been in the press during the week. Because excitement is a rather subjective feeling, we aim to have it written by a different PhD student every week! We would also love to hear what you think about the science that’s been in the news. Let us know in the comments below!  Continue reading “This Week’s Top 3 Science News (8/2 to 15/2)”

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